pathway modelling of glycolysis in gnowsys

As final year project of B.Tech in Bioinformatics, Pradnya, Lakshmi, Thara students from D. Y . Patil  Institute of Biotechnology and Bioinformatics, Navi Mumbai, worked on a project on representing pathway modelling of glycolysis in gnowsys. The project involved to create dictionaries, store into gnowsys and then represent using graphviz. The project report can be viewed from the trac site.

The glycolysis pathway is represented using the transformations that each molecule undergoes. For e.g. the glucose 6 phosphate gets transformed into fructose 6 phosphate as a result of phosphorylation. Such processes in glycolysis have been mapped to represent the pathway.

process modelling of mitosis in gnowsys

As final year project of B.Tech in Bioinformatics, Ruchi student from D.Y . Patil from D. Y . Patil Institute of Biotechnology and Bioinformatics, Navi Mumbai, worked on a project on representing processes modelling of mitosis in gnowsys. The project involved to create dictionaries, store into gnowsys and then represent using graphviz. The project report can be viewed from the trac site.

The mitotic process has been represented in the form of prior-state and post-state. For e.g. in prophase, the chromatin’s prior state is thin, fibre-like and its post state is thick, condensed form. In this case, the chromatin’s properties are getting changed. In this way, we have modelled each change in the structural objects by representing the changes in the states of the object.